Do any reach 8-12 pounds or so? Do they have specific health problems, in general? Is their temperment so different from Yorkies as I've had 3 and they've all loved people and other pets?

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Although the standard is 4 - 7 lbs, some do indeed reach 8 - 12 lbs. There is a difference in the Yorkie and Biewer personalities. The yorkie can be more independent and stand-offish. but both are wonderful pets.